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Wednesday, May 13, 2020 | History

3 edition of Calcium antagonists. found in the catalog.

Calcium antagonists.

by W. G. Nayler

  • 91 Want to read
  • 18 Currently reading

Published by Academic in London .
Written in English

    Subjects:
  • Calcium -- Antagonists -- Therapeutic use.

  • Classifications
    LC ClassificationsRM666.C24
    The Physical Object
    Pagination(250)p.
    Number of Pages250
    ID Numbers
    Open LibraryOL22366449M
    ISBN 100125146450

    You don't need to worry about taking a daily calcium supplement with a calcium-channel blocker. In the body, calcium not only builds bones but also powers muscle contractions. Calcium-channel blockers lower blood pressure by reducing the amount of calcium available to contract blood vessels.   The calcium channel antagonists are not an homogeneous group. From both pharmacological and clinical points of view, they can be divided into those of the dihydropyridine family like nifedipine, and those of the non-dihydropyridine family like verapamil and by:

    Calcium antagonists have recently emerged as an important class of drugs in the treatment of cardiovascular disorders. They signify a major advance in drug therapy. They are a heterogeneous group of compounds that have been called by a variety of names: calcium entry blockers, calcium influx blockers, slow channel blockers, calcium blockers, and calcium by: 9. This causes the blood vessels to relax and widen, which allows the blood to flow more easily and lowers blood pressure. Some calcium antagonists may also slow the heartbeat. Calcium antagonists are used to treat high blood pressure, chest pain (angina), abnormal heartbeat (arrhythmia), and several other conditions. Also called calcium channel.

      This chapter book fills that gap. The book reviews in detail the biochemical and pharmacokinetics of calcium channel blockers and their clinical role in the therapy of hypertension, heart failure, myocardial infarction, arrhythmias, gastrointestinal pathology, pulmonary disorders, and cerebrovascular : Mihai Gheorghiade. Calcium antagonists are a type of drug that block calcium channels in cells and are often used for the treatment of high blood pressure. They have also been shown to counteract the narrowing of blood vessels after subarachnoid haemorrhage and to protect the brain against periods of ischaemia.


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Calcium antagonists by W. G. Nayler Download PDF EPUB FB2

Michael Prisant, in Hypertension (Second Edition), Calcium antagonists are commonly used antihypertensive drugs among prescribing physicians. 1–4 In the Cardiovascular Health Study, there was an increase in the use of calcium antagonists from 14% in to 36% in among participants aged 65 years or older (Figure ).

4 Calcium antagonists. book growth of calcium antagonist use has been. Some calcium channel blockers have the added benefit of slowing your heart rate, which can further lower your blood pressure, relieve chest pain (angina) and control an irregular heartbeat.

Calcium channel blockers are also called calcium antagonists. This book presents the results of experimental studies of the effect of calcium antagonists on nephrocalcinosis and acute renal failure after ischemia. In this context, the clinician is particularly interested in the use of calcium antagonists to protect against the kidney in urolithiasis, in acute renal failure and during kidney : Paperback.

Calcium-channel blockers, also called calcium antagonists, inhibit transmembrane calcium influx in cardiac and vascular smooth muscle, leading to vasodilation and lowering of blood decreasing the calcium influx, the heart’s contraction becomes less forceful, reducing heart rate, relaxing and opening up narrowed blood vessels, and lowering blood pressure [22,23].

Although the importance of calcium (Ca 2+) in the maintenance of cardiac contractility was recognized as early asCalcium antagonists.

book critical role of the ion in the contractile process in skeletal, cardiac, and smooth muscle has only been established within the last three decades. As the complexity of the pharmacological actions of the Ca 2+ channel inhibitors grows, there is a continued need to Format: Paperback.

Inhibition of Human Platelet Aggregation and Calcium-Dependent, Phospholipase A2 Activity by Calcium Antagonists: Evidence for Intracellular Effects of Calcium Slow Channel Blockers.

Pages Franson, Richard C. (et al.). Additional Physical Format: Online version: Nayler, Winifred G. Calcium antagonists. London ; San Diego: Academic Press, (OCoLC) Document Type. ISBN: OCLC Number: Description: viii, pages: illustrations ; 24 cm: Contents: Biochemical and pharmacological differences among calcium antagonists: clinical implications / David J.

Triggle --Calcium function in vascular smooth muscle and its relationship to hypertension / Jeffrey L. Ram, Paul R. Standley, James R. Sowers --Pharmacokinetics of calcium. Calcium-channel blockers are a medication often used to treat high blood pressure. UK blood pressure charity information about calcium channel blockers, side effects and using them.

Calcium blockers Skip the primary navigation if you do not want to read it as the next section. Primary navigation. Abstract.

1 The Ca 2+ antagonists are a novel group of drugs useful in management of a variety of cardiac disorders. They differ from one another in terms of their chemistry, tissue specificity and selectivity. As a group, however, they share the common property of slowing Ca 2+ entry through voltage-activated, ion-selective channels.

Some of them exhibit other properties, including that of Cited by: This book presents the results of experimental studies of the effect of calcium antagonists on nephrocalcinosis and acute renal failure after ischemia.

In this context, the clinician is particularly interested in the use of calcium antagonists to protect against the kidney in urolithiasis, in acute renal failure and during kidney : Springer Berlin Heidelberg.

Middleton E., Jr Role of calcium and calcium antagonists in airway function. Eur J Respir Dis Suppl. ; (Pt 1)– Middleton E, Jr, Drzewiecki G, Triggle D.

Effects of smooth muscle calcium antagonists on human basophil histamine release. Biochem Pharmacol. Oct; 30 (20)–Cited by: Find many great new & used options and get the best deals for Second Generation of Calcium Antagonists by W.

Nayler (, Paperback) at the best online prices at. The book also includes important uses of Ca 2+ antagonists in novel areas of interest such as the gastrointestinal tract, renal protection and multi-drug resistance. Keywords atherosclerosis calcium cardiovascular clinical research drug resistance heart hypertension.

calcium channel blocker (calcium channel blocking agent) a drug such as nifedipine, diltiazem, or verapamil that selectively blocks the influx of calcium ions through a calcium channel of cardiac muscle and smooth muscle cells; used in the treatment of Prinzmetal's angina, chronic stable angina, and cardiac m channel blocking agents act to control arrhythmias by slowing the.

Search within book. Physiological Significance of Calcium: Calcium Antagonism. Helmut Lydtin, Peter Trenkwalder. Pages Chemical Structure and Pharmacokinetics of Calcium Antagonists.

Helmut Lydtin, Peter Trenkwalder. Pages Pharmacological Effects of Calcium Antagonists. Helmut Lydtin, Peter Trenkwalder. Pages Examples of calcium antagonist in a sentence, how to use it. 14 examples: Terodiline was widely used in the treatment of incontinence, having calcium.

Short Acting Calcium Channel Blockers. Findings. Myocardial Infarction Risk: 60% over Diuretics; Higher dose confers >3x risk of lower dose; References. Psaty () JAMA[PubMed]. class of drugs that act by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools; since they are inducers of vascular and other smooth muscle relaxation, they are used in the drug therapy of hypertension and cerebrovascular spasms, as myocardial protective agents, and in.

Calcium Antagonists and Central Nervous System Diseases (Alexander Scriabine, MD) CALCIUM ANTAGONISTS AND THE KIDNEY Renal Hemodynamic Effects of Calcium Antagonists (Koichi Hayashi, MD, PhD, Takao Saruta, MD, PhD, and Murray Epstein, MD, FACP).

Drugs classified as calcium antagonists or calcium-channel blockers were introduced into clinical medicine in the s and are now among the most frequently prescribed drugs for the treatment of c Cited by:   As a group, calcium antagonists cause vascular dilation and do not cause bronchial constriction, in contrast to the beta-adrenoceptor blocking agents.

In many patients these diverse properties allow safe combination of calcium antagonists and beta-adrenoceptor blockers if Cited by: The calcium channel antagonists inhibit calcium uptake into cells through a channel in the cell membrane which is specific for the entry of divalent cations particularly calcium.

The result of this inhibition is to reduce the availability of intracellular calcium and thus interfere with Cited by: